The answer is MINUS eight pi alpha.
The Big Bang Theory Season 1, Episode 13
extends to MINUS infinity
in time.
The Big Bang Theory Season 12, Episode 5
...MINUS 21 men
before the loss of virginity...
The Big Bang Theory Season 4, Episode 1
Yeah, MINUS five,
The Big Bang Theory Season 11, Episode 12
T Minus 45 seconds!
The Big Bang Theory Season 7, Episode 14